Chemical Synthesis of Materials

Researchers: Daryl Yee (Ph.D. student in Materials Science), Luizetta Navrazhnyukh (Ph.D. student in Medical Engineering), Namita Sarraf (Ph.D. student in BioEngineering)

DNA functionalized structures for drug capture

This group's focus lies in synthesizing functional resins which can be used in two-photon lithography and 3D printing to fabricate cross-linked architectures with a variety of chemical functionalities, which range from surface functional ligands (i. e. thiols, N-BOC, octane, aromatics, DNA, pharmaceutical compounds, etc.) to shape-memory polymers, whose shape can be programmed at a particular temperature and then mechanically altered, to DNA origami that can be used for large-area nano-patterning.

Fabrication of functionalized 3D structures

This architectural versatility renders these 3D polymer structures useful for many technological applications, including drug delivery and tissue engineering. Synthesizing and architecting these meta-materials with the right chemical functionality on the surface and/or in the volume presents a significant challenge. We are developing such architected, chemically-functionalized 3D meta-materials that are responsive to external stimuli and are exploring the specific role that architecture plays on their behavior and how to harness these effects to engineer new multi-functional devices.